吴彬

发布者:赵林霞发布时间:2019-10-31动态浏览次数:777

吴彬,生物信息工程博士。20109月至201611月在上海大学生命科学学院神经药理毒理实验室学习,获博士学位。201611月至20197月在美国印第安纳大学医学院Stark神经生物中心从事研究工作。201910月进入南通大学特种医学研究院工作。

研究方向:

慢性疼痛的分子和电生理机制。

代表性论文:

1.Su, X., Wu, B., Zhang, W., Ji, Y.-H., Wang, Q., and Tan, Z.-Y. (2020) Inhibitory Effects of Columbianadin on Nociceptive Behaviors in a Neuropathic Pain Model, and on Voltage-Gated Calcium Currents in Dorsal Root Ganglion Neurons in Mice, Frontiers in Pharmacology 10. (共同一作)

2.Wu, B., McDermott, J. S., Krajewski, J. L., Knopp, K. L., Nisenbaum, E. S., Cummins, T. R., and Tan, Z. Y. (2019) Extracellular signal-regulated kinases mediate the enhancing effects of inflammatory mediators on resurgent currents in dorsal root ganglion neurons, Molecular pain 15, 1744806919837104.

3.Zhou, J., Feng, D., Zhang, X., Xia, C., Zhang, Z., Kang, J., Tan, Z., and Wu, B. (2019) Involvement of P2X7 receptors in satellite glial cells of dorsal root ganglia in the BmK I -induced pain model of rats, Gen Physiol Biophys 38, 407-416. (通讯作者)

4.Zhou, J., Zhang, X., Zhou, Y., Wu, B., and Tan, Z. Y. (2019) Up-regulation of P2X7 Receptors Contributes to Spinal Microglial Activation and the Development of Pain Induced by BmK-I, Neuroscience bulletin 35, 624-636.

5.Li, Z. W., Wu, B., Ye, P., Tan, Z. Y., and Ji, Y. H. (2016) Brain natriuretic peptide suppresses pain induced by BmK I, a sodium channel-specific modulator, in rats, The journal of headache and pain 17, 90.

6.Wu, B., Wu, B. F., Feng, Y. J., Tao, J., and Ji, Y. H. (2016) Mapping the Interaction Anatomy of BmP02 on Kv1.3 Channel, Scientific reports 6, 29431.

7.Wu, B., Zhu, Y., Shi, J., Tao, J., and Ji, Y. (2016) BmP02 Atypically Delays Kv4.2 Inactivation: Implication for a Unique Interaction between Scorpion Toxin and Potassium Channel, Toxins 8.

8.Tao, J., Zhou, Z. L., Wu, B., Shi, J., Chen, X. M., and Ji, Y. H. (2014) Recombinant expression and functional characterization of martentoxin: a selective inhibitor for BK channel (alpha + beta4), Toxins 6, 1419-1433.